Reactivation of Herpes Simplex Virus Infection by Ultraviolet Light and Possible Involvement of Prostaglandins
- 1 December 1976
- journal article
- research article
- Published by Microbiology Society in Journal of General Virology
- Vol. 33 (3) , 547-550
- https://doi.org/10.1099/0022-1317-33-3-547
Abstract
Herpes simplex infection in the mouse ear was used to investigate whether various treatments would reactivate the disease. Immunosuppressive drugs failed to induce clinical signs of reactivation but irradiation of the skin of the originally infected ear with UV light or injection of prostaglandin E2 or PBSA into this site, caused reactivation of infection. This was detected by the appearance of infectious virus in the skin 2-3 days after these treatments. The results are discussed in relation to the mechanism of herpes reactivation in man.This publication has 2 references indexed in Scilit:
- AN ALTERNATIVE THEORY OF HERPES-SIMPLEX RECURRENCE AND A POSSIBLE ROLE FOR PROSTAGLANDINSThe Lancet, 1976
- Pathogenesis Of Recurrent Herpes Simplex InfectionsJournal of Investigative Dermatology, 1975