Metabolism of sulphur

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Abstract
Du Vigneaud''s basal diet was used with 6% casein as the basal protein in the cystine-deficient diet and 15% arachin in the methionine-deficient diet. Albino rats on the cystine-deficient diet indicated the following quantitative metabolic relationships as expressed by growth curves: One molecule of 1-cystine is available from three molecules of 1-cystine disulphoxide, and is equivalent to 2 molecules of 1-cysteine or 2 molecules of 1-methionine. Rats on the methionine-deficient diet indicated that dl-methionine is somewhat less readily utilized for growth than the 1 form; 1-methionine definitely increases the utilization of food for growth. Absolute amts. of methionine and cystine which, under these conditions, permit normal growth in yoUng albino rats on an otherwise adequate diet, are estimated.

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