A New Method for the Study of Chromosome Rearrangements and the Plotting of Chromosome Maps

Publisher Website
Google Scholar
Abstract
The author found in the salivary glands of Drosophila melanogaster and other Diptera a chromosome morphology which makes it possible to determine, in cases of dislocation of parts, the exact point or points of breakage, and the exact new position of the part dislocated. This gives in Diptera a new method of qualitative morphological chromosome analysis, and more accurate knowledge of gene loci and chromosome map construction. Each chromosome is composed of segments, and each segment has a characteristic pattern of lines and bands. Each chromosome has its own characteristic pattern of segments, lines, and bands which is maintained in different cells and in every individual. In old larvae somatic synapsis occurs. Cases of inversion or loss of a part are evidenced by typical inversion figures and buckling respectively; and this enables the determination of what parts are inverted or missing in a homologue. The inert portions of both X & Y chromosomes appear to be lacking. A diagram of the X chromosome with its segments, lines and bands shows the loci of various genes. Detailed articles to follow.

This publication has 0 references indexed in Scilit: