Hypertrophic Cardiomyopathy in Cardiac Myosin Binding Protein-C Knockout Mice
Top Cited Papers
- 22 March 2002
- journal article
- research article
- Published by Wolters Kluwer Health in Circulation Research
- Vol. 90 (5) , 594-601
- https://doi.org/10.1161/01.res.0000012222.70819.64
Abstract
Familial hypertrophic cardiomyopathy (FHC) is an inherited autosomal dominant disease caused by mutations in sarcomeric proteins. Among these, mutations that affect myosin binding protein-C (MyBP-C...Keywords
This publication has 31 references indexed in Scilit:
- A role for C‐protein in the regulation of contraction and intracellular Ca2+ in intact rat ventricular myocytesThe Journal of Physiology, 2000
- Impaired cardiomyocyte relaxation and diastolic function in transgenic mice expressing slow skeletal troponin I in the heartThe Journal of Physiology, 1999
- Mutations in β-myosin S2 that cause familial hypertrophic cardiomyopathy (FHC) abolish the interaction with the regulatory domain of myosin-binding protein-CJournal of Molecular Biology, 1999
- A mouse model of myosin binding protein C human familial hypertrophic cardiomyopathy.Journal of Clinical Investigation, 1998
- Derivation of completely cell culture-derived mice from early-passage embryonic stem cells.Proceedings of the National Academy of Sciences, 1993
- Alterations in Ca2+ sensitive tension due to partial extraction of C-protein from rat skinned cardiac myocytes and rabbit skeletal muscle fibers.The Journal of general physiology, 1991
- Interaction of C-protein with pH 8.0 synthetic thick filaments prepared from the myosin of vertebrate skeletal muscleJournal of Muscle Research and Cell Motility, 1988
- H-protein and X-proteinJournal of Molecular Biology, 1983
- Phosphorylation of a myofibrillar protein of Mr 150 000 in perfused rat heart, and the tentative identification of this as C‐proteinFEBS Letters, 1980
- A new protein of the thick filaments of vertebrate skeletal myofibrilsJournal of Molecular Biology, 1973