Regioselective cleavage of aromatic methyl ethers by methanesulphonic acid in the presence of methionine
- 1 January 1977
- journal article
- research article
- Published by Royal Society of Chemistry (RSC) in Journal of the Chemical Society, Perkin Transactions 1
- No. 20,p. 2288-2289
- https://doi.org/10.1039/p19770002288
Abstract
Addition of methionine as a methyi group accept or facilitates acidolysis of aromatic methyl ethers such as anisole and p-methoxytoluene. Veratraldehyde and 4,5-dimethoxyindan-1-one gave isovanilin and 4-hydroxy-5-methoxyindan-1-one, respectively, indicating the usefulness of the reagent for regioselective cleavage.Keywords
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