EFFECT OF DIETARY SUPPLEMENTATION OF VITAMIN-E ON SERUM-LIPIDS AND LIPOPROTEINS IN RABBITS FED A CHOLESTEROLEMIC DIET

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  • 1 January 1979
    • journal article
    • research article
    • Vol. 49  (4) , 370-375
Abstract
The effect of dietary supplementation of vitamin E on serum cholesterol, triglycerides, lipoproteins and lipoprotein composition was studied in rabbits fed 1% cholesterol diet for 12 wk. Vitamin E supplemented animals maintained significantly lower concentrations of serum cholesterol, triglycerides and very low density lipoproteins (d < 1.006). The difference in the serum lipid content was mainly in the very low density lipoproteins of d < 1.006. The possibility of an increased clearance of chylomicron remnants and decreased inhibition of extrahepatic lipoprotein lipase in hypercholesterolemic rabbits as a result of vitamin E supplementation is discussed in the light of the results.

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