Interferon inhibits the redistribution of cell surface components.
Open Access
- 31 July 1980
- journal article
- research article
- Published by Rockefeller University Press in The Journal of Experimental Medicine
- Vol. 152 (2) , 469-474
- https://doi.org/10.1084/jem.152.2.469
Abstract
Interferon treatment impairs the ability of cells to redistribute cell surface receptors for concanavalin A (Con A). The effect of interferon becomes evident within 3-6 h and is maximal within 36-48 h. Highly purified human fibroblast interferon (> 2 x 10(8) U/mg of protein sp act; concentration; 640 U/ml) caused approximately 85% inhibition of capping of fluorescein-conjugated Con A in interferon-sensitive HeLa-S3 cells at 36 h from the beginning of treatment.This publication has 16 references indexed in Scilit:
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