Abstract
Protein variation controlled by 28 genetic loci was analyzed in samples from 3 island and 3 mainland populations of the white-footed mouse, P. leucopus. Nine of the 28 loci have polymorphic alleles in 1 of more of the populations. Island populations were less genetically variable than mainland populations. Estimated heterozygosity (.hivin.H) had a mean value of 7.1% for island populations and 8.0% for mainland populations. The proportion of loci polymorphic (P) for island and mainland populations corresponded to 21.4 and 32.1%, respectively. Coefficients of genetic similarity (S) for paired geographical populations ranged from 0.92-0.99.

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