BAli-Phy: simultaneous Bayesian inference of alignment and phylogeny
Open Access
- 5 May 2006
- journal article
- research article
- Published by Oxford University Press (OUP) in Bioinformatics
- Vol. 22 (16) , 2047-2048
- https://doi.org/10.1093/bioinformatics/btl175
Abstract
Summary: BAli-Phy is a Bayesian posterior sampler that employs Markov chain Monte Carlo to explore the joint space of alignment and phylogeny given molecular sequence data. Simultaneous estimation eliminates bias toward inaccurate alignment guide-trees, employs more sophisticated substitution models during alignment and automatically utilizes information in shared insertion/deletions to help infer phylogenies. Availability: Software is available for download at . Contact:msuchard@ucla.eduKeywords
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