TNF‐α increases ubiquitin‐conjugating activity in skeletal muscle by up‐regulating UbcH2/E220k
Open Access
- 8 April 2003
- journal article
- research article
- Published by Wiley in The FASEB Journal
- Vol. 17 (9) , 1048-1057
- https://doi.org/10.1096/fj.02-0759com
Abstract
In some inflammatory diseases, TNF-α is thought to stimulate muscle catabolism via an NF-κB-dependent process that increases ubiquitin conjugation to muscle proteins. The transcriptional mechanism of...Keywords
Funding Information
- National Institutes of Health (DK02707, HL59878)
- National Space Biomedical Research Institute
- Muscular Dystrophy Association
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