DISTURBANCES IN SODIUM CHLORIDE METABOLISM

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Abstract
Recent investigations have brought to light many interesting facts concerning the morbid processes that may result from disturbances in sodium chloride metabolism. In the past it was recognized in a vague fashion that sodium chloride must have something to do with the osmotic pressure relationship in the blood and tissues. Further than that there has been very little appreciation of the extreme importance of this inorganic salt in the animal body. GENERAL CONSIDERATIONS The blood normally contains about 500 mg. of sodium chloride per hundred cubic centimeters and all the tissues contain varying quantities, so that the adult of average size will carry in his body approximately 300 Gm. of salt as a necessary requirement for life. Furthermore, the gastro-intestinal tract is normally a reservoir of surplus sodium chloride. In addition to the fact that there are appreciable quantities of salt in many of the foods that are taken, man

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