Autoimmune phenomena in infertile patients with endometriosis

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Abstract
Recent data in the literature suggest that endometriosis may lead to an autoimmune reaction. This is supported by the presence of excess macrophage reaction in the peritoneal fluid of these patients1. In addition, immunofluorescence studies have shown the presence of complement component C3 in the endometrium of patients with endometriosis2. It has been hypothesized that protein substances from the ectopic endometrial tissue is recognized as foreign and stimulate the immune reaction. The present study examines the concentration of complement components C3c and C4, properdin, factor B, and immunoglobulins in the peritoneal fluid and serum of infertile patients with endometriosis. The results are compared with those with no evidence of endometriosis. Keywords Alternative Pathway Complement System Peritoneal Fluid Protein Substance Complement Component These keywords were added by machine and not by the authors. This process is experimental and the keywords may be updated as the learning algorithm improves.