ELEVATED SALIVARY IODINE AND SALIVARY GLAND ENLARGEMENT DUE TO IODINATED CONTRAST MEDIA

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Abstract
After each of 3 intravenous urographic examinations a patient with advanced renal failure developed salivary gland enlargement. Total iodine and free iodide concentrations were measured in mixed saliva and in plasma collected while he had sialadenopathy. These measurements revealed high concentrations of both organically bound iodine and free iodide in the saliva at a time when the plasma diatrizoate level was high. The findings suggest secretion of contrast media by the salivary glands, concomitant with the secretion of free iodine split off of the organic contrast molecule.

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