TheKlebsiella-Enterobacter-SerratiaDivision
- 1 December 1966
- journal article
- research article
- Published by American College of Physicians in Annals of Internal Medicine
- Vol. 65 (6) , 1180-1194
- https://doi.org/10.7326/0003-4819-65-6-1180
Abstract
Clinical and epidemiological characteristics of 247 patients infected with Klebsiella, Enterobacter and Serratia were correlated with the species and capsular types of these genera of Enterobacteriaceae. Seventy-five percent of the patients were infected with K. pneumonia (38 capsular types): of the remainder, 24 had non-typeable Klebsiella, 24 had E. cloacea, 15 had E. aerogenes and 3 had Serratia infections. The patients generally were elderly, suffered from other medical or surgical illnesses, received previously antibiotic treatment, and had functional or structural abnormalities of the urinary tract. The etiologic role of these organisms was uncertain in many of the patients except in those with bacteremia, demonstrated in 25%. The mortality among all 247 patients was 12%; am ong the bacteremia patients it was aoout 50%; only 1 of 6 patients with bacteremia accompanying infection of the respiratory tract survived. K. pneumoniae type 24 was the most common type isolated and and was endemic at this hospital during the time of the study. This was most often associated with urinary tract infections, was considered to be hospital-acquired and was the most resistant to the antibiotics in common use within the hospital.Keywords
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