N-Acetylation Phenotype in Bladder Cancer

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Abstract
1 N-acetylation phenotype has been examined in 30 patients with bladder cancer and in 27 controls of similar age. 2 59% of controls and 70% of bladder cancer patients were phenotypically 'slow' acetylators. This difference was not significant ( P>0.30) . 3 Within phenotypes, isoniazed half life was similar in controls and bladder cancer patients. 4 N-acetylation phenotype is unlikely to be a major determinant in the pathogenesis of bladder cancer in the population studied.