Rectal diazepam in the treatment of absence status: a pharmacodynamic study
- 1 October 1981
- journal article
- research article
- Published by BMJ in Journal of Neurology, Neurosurgery & Psychiatry
- Vol. 44 (10) , 914-917
- https://doi.org/10.1136/jnnp.44.10.914
Abstract
Rectal administration of diazepam is highly effective in terminating absence status in humans as judged by reduction of spike-wave activity in the EEG. Pharmacokinetic studies indicate that diazepam can have antiepileptic properties at serum levels well below those reported as being necessary to achieve a therapeutic effect.This publication has 13 references indexed in Scilit:
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