The steroid antagonist RU38486 is metabolized by the liver microsomal P450 mono-oxygenases
- 1 March 1990
- journal article
- research article
- Published by Elsevier in Biochemical and Biophysical Research Communications
- Vol. 167 (3) , 1271-1278
- https://doi.org/10.1016/0006-291x(90)90661-6
Abstract
No abstract availableThis publication has 10 references indexed in Scilit:
- Plasma concentrations and receptor binding of RU 486 and its metabolites in humansPublished by Elsevier ,2003
- Expression of a constitutive form of cytochrome P450 during rat‐liver development and sexual maturationEuropean Journal of Biochemistry, 1988
- Interactions of hepatic cytochromes P-450 with steroid hormones: Regioselectivity and stereospecificity of steroid metabolism and hormonal regulation of rat P-450 enzyme expressionBiochemical Pharmacology, 1988
- Expression of cytochromes P-450 in rat hepatoma cells. Analysis by monoclonal antibodies specific for cytochromes P-450 from rat liver induced by 3-methylcholanthrene or phenobarbitalEuropean Journal of Biochemistry, 1984
- An approach to the mechanism of the potent antiglucocorticoid: 17β-hydroxy- 11β -4-dimethylaminophenyl-17α- propynyl-estra-4,9-dien-3-oneThe Journal of Steroid Biochemistry and Molecular Biology, 1984
- RU 38486: Potent antiglucocorticoid activity correlated with strong binding to the cytosolic glucocorticoid receptor followed by an impaired activationJournal of Steroid Biochemistry, 1984
- STUDIES OF METABOLISM OF DIETHYL PARA-NITROPHENYL PHOSPHOROTHIONATE (PARATHION) AND BENZPHETAMINE USING AN APPARENTLY HOMOGENEOUS PREPARATION OF RAT-LIVER CYTOCHROME-P-450 - EFFECT OF A CYTOCHROME-P-450 ANTIBODY PREPARATION1976
- SPECTRAL STUDIES OF DRUG INTERACTION WITH HEPATIC MICROSOMAL CYTOCHROME1967
- The Carbon Monoxide-binding Pigment of Liver MicrosomesJournal of Biological Chemistry, 1964
- PROTEIN MEASUREMENT WITH THE FOLIN PHENOL REAGENTJournal of Biological Chemistry, 1951