EFFECT OF PROSTAGLANDINS-F2ALPHA AND E2 ON MILK EJECTION, BLOOD-PRESSURE AND MAMMARY ARTERY BLOOD-FLOW IN COW

  • 1 January 1977
    • journal article
    • research article
    • Vol. 227  (1) , 159-161
Abstract
Injections of prostaglandins [PG] F2.alpha. (threshold dose: 1-5 .mu.g) and E2 (threshold dose: 100-300 .mu.g) in the jugular vein or the carotid artery induced milk ejection in lactating cows after a relatively long latency period. In several cases with PGF2.alpha. and in 1 case with PGE2 milk ejection was accompanied by a simultaneous increase in blood flow through the mammary artery. Both routes of administration showed the same response. The effect of the PG on milk ejection apparently is indirect, possibly secondary to a release of oxytocin from the neurohypophysis.

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