Xamoterol improves the Control of Chronic Atrial Fibrillation in Elderly Patients

Publisher Website
Google Scholar
Abstract
Twenty digitalized elderly patients with chronic atrial fibrillation were randomized into a double-blind crossover study. None was in overt heart failure and all were taking 1.5 s was significantly reduced by xamoterol alone. Walking distance in 6 minutes was 406.1 ± 27.1 m (mean + SE) at baseline and improved significantly on both treatments (450.3 ± 19.8 on xamoterol; p < 0.02 and 453.7 ± 19.2 on xamoterol plus digoxin; p < 0.01). No significant change was found in subjective measurements of palpitations, breathlessness and well-being using visual analogue scales. Xamoterol combined with digoxin improves effort tolerance and heart-rate control by reducing diurnal tachycardia and nocturnal bradycardia and pauses.

This publication has 0 references indexed in Scilit: