Effect of Coprinus atramentarius on the metabolism of ethanol in mice
- 1 March 1969
- journal article
- Published by Oxford University Press (OUP) in Journal of Pharmacy and Pharmacology
- Vol. 21 (3) , 176-179
- https://doi.org/10.1111/j.2042-7158.1969.tb08223.x
Abstract
The ethanol-soluble material extracted from Coprinus atramentarius was more toxic to mice, as measured by the LD50 and potentiation of the ethanol-induced sleeping time, than the whole mushroom or the residue remaining after ethanol extraction. Also, the ethanol-soluble fraction when fed to mice 4 h before administration of ethanol markedly increased the blood acetaldehyde and ethanol levels.Keywords
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