Cyclosporine in the Treatment of Red Cell Aplasia
- 1 January 1987
- journal article
- case report
- Published by Wolters Kluwer Health in Journal of Pediatric Hematology/Oncology
- Vol. 9 (4) , 314-316
- https://doi.org/10.1097/00043426-198724000-00007
Abstract
A 4-year-old girl was diagnosed to have pure red cell aplasia. For 5 years, she received multiple packed red cell transfusions (average 11/year). Several therapeutic maneuvers were attempted including prednisone, oxymethalone, plasmaphoresis, high dose methyl prednisolone-to no avail. Finally, cyclosporine was administered for 5 months. This increased her reticulocyte count and cured the disease. For the last 2 years she has been in excellent health and has not required any further transfusions. The possible mechanism of action of cyclosporine in this disease is discussed.Keywords
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