STUDIES ON THE CHEMOTHERAPY OF THE HUMAN MALARIAS. I. METHOD FOR THE QUANTITATIVE ASSAY OF SUPPRESSIVE ANTIMALARIAL ACTION IN VIVAX MALARIA 123

Abstract
A standard procedure suitable for the quantitative appraisal of drug activity in blood-induced vivax malaria is descr. The close relationship between plasma quinine concn. and therapeutic response makes possible the quantitative appraisal of drug activity with a limited number of exptl. subjects. By means of this procedure, it was demonstrated that the quinine susceptibility of the erythrocytic phase of vivax malaria is a stable strain characteristic and that it is independent of the mode by which the malaria is transmitted.

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