Induction and Isolation of Artemisinine-Resistant Mutants of Plasmodium falciparum
- 1 May 1985
- journal article
- Published by American Society of Tropical Medicine and Hygiene in The American Journal of Tropical Medicine and Hygiene
- Vol. 34 (3) , 417-418
- https://doi.org/10.4269/ajtmh.1985.34.417
Abstract
Five artemisinine-resistant mutants of Plasmodium falciparum have been isolated from a cloned parent following mutagenic treatment with N-methyl-N′-nitronitrosoguanidine. This observation may influence the strategy of the use of artemisinine or its derivatives. Mutant isolation should prove useful in the study of drug resistance to other antimalarials.Keywords
This publication has 0 references indexed in Scilit: