CD4 cell recovery during successful antiretroviral therapy in naive HIV-infected patients
- 1 November 2004
- journal article
- research article
- Published by Wolters Kluwer Health in AIDS
- Vol. 18 (16) , 2210-2212
- https://doi.org/10.1097/00002030-200411050-00018
Abstract
We evaluated the impact of HIV risk practice on immune reconstitution in a prospective cohort of 288 patients (176 former injecting drug users) who maintained complete virus suppression for more than 24 months. Significant differences in CD4 cell counts at 6 and 24 months were detected. Multivariate analysis showed that drug use was an independent predictor of poor immunological recovery. Injection drug abuse impairs short and long-term CD4 cell recovery in HIV-positive patients initiating successful highly active antiretroviral therapy.Keywords
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