Subtilin-An Antibiotic Produced by Bacillus subtilis. I. Action on Various Organisms.
- 1 October 1945
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 60 (1) , 60-64
- https://doi.org/10.3181/00379727-60-15091
Abstract
The antibacterial product, subtilin, obtained from Bacillus subtilis, was found to be active chiefly against Gram-positive bacteria. Two notable exceptions to the rule were Neisseria catarrhalis and N. gonorrhoeae, both Gram-negative, but also antagonized by subtilin. Acid-fast organisms, including Myco-bacterium tuberculosis, were also found to be susceptible to the antibiotic. The agent produced a bacteriostatic action in high dilution and a germicidal effect in greater conc. Several pathogenic higher fungi were also found to be susceptible to subtilin.Keywords
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