Allantoin excretion in the rat

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Abstract
1. Allantoin excretion was determined in forty-four rats; twenty-four rats were 21 d old and twenty were 90 d old. The animals receivedad lib.for 11 d diets that contained varying amounts of protein from casein and from gluten. Urinary allantoin excretion was determined during the last 3 d of the period.2. The amount of allantoin excreted in both young and adult animals was independent of the diet consumed and was related to metabolic weight (W in kg0·73) and rate of gain in body-weight (ΔW in g/d), also to body nitrogen content (N in g0·73) and rate of gain in body N (ΔN in mg/d), according to the equations allantoin (mg/d) = 60·54 W0·73+ 2·12ΔW, and allantoin (mg/d) = 5·45 N0·73+ 0·071ΔN.