Induction of differentiation of leukaemic (HL‐60) or prostate cancer (LNCaP, JCA‐1) cells potentiates apoptosis triggered by onconase
Open Access
- 1 December 2000
- journal article
- research article
- Published by Wiley in Cell Proliferation
- Vol. 33 (6) , 407-417
- https://doi.org/10.1046/j.1365-2184.2000.00186.x
Abstract
Onconase (Onc) is a ribonuclease from amphibian oocytes that is cytostatic and cytotoxic to many tumour lines. It shows in vivo antitumour activity in mouse tumour models and is currently in Phase II...Keywords
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