Cytoplasmic dynein could be key to understanding neurodegeneration
Open Access
- 1 January 2008
- journal article
- review article
- Published by Springer Nature in Genome Biology
- Vol. 9 (3) , 214
- https://doi.org/10.1186/gb-2008-9-3-214
Abstract
A new mouse mutation, Sprawling, highlights an essential role for the dynein heavy chain in sensory neuron function, but it lacks the ability of other known heavy-chain mutations to ameliorate neurodegeneration due to defective superoxide dismutase.Keywords
This publication has 21 references indexed in Scilit:
- Proprioceptive Sensory Neuropathy in Mice with a Mutation in the Cytoplasmic Dynein Heavy Chain 1 GeneJournal of Neuroscience, 2007
- SNX4 coordinates endosomal sorting of TfnR with dynein-mediated transport into the endocytic recycling compartmentNature Cell Biology, 2007
- Force-Induced Bidirectional Stepping of Cytoplasmic DyneinCell, 2007
- Retrolinkin, a membrane protein, plays an important role in retrograde axonal transportProceedings of the National Academy of Sciences, 2007
- Dynein is required for receptor sorting and the morphogenesis of early endosomesNature Cell Biology, 2006
- Dazl can bind to dynein motor complex and may play a role in transport of specific mRNAsThe EMBO Journal, 2006
- Genetic Analysis of the Cytoplasmic Dynein Subunit FamiliesPLoS Genetics, 2006
- Interaction of the Postsynaptic Density-95/Guanylate Kinase Domain-Associated Protein Complex with a Light Chain of Myosin-V and DyneinJournal of Neuroscience, 2000
- The Proapoptotic Activity of the Bcl-2 Family Member Bim Is Regulated by Interaction with the Dynein Motor ComplexMolecular Cell, 1999
- Cytoplasmic dynein and dynactin in cell division and intracellular transportCurrent Opinion in Cell Biology, 1999