Tenascins: regulation and putative functions during pathological stress
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- 1 July 2003
- journal article
- review article
- Published by Wiley in The Journal of Pathology
- Vol. 200 (4) , 488-499
- https://doi.org/10.1002/path.1415
Abstract
In this review, we discuss the structure and function of the extracellular matrix protein family of tenascins with emphasis on their involvement in human pathologies. The article is divided into the following sections: Introduction: the tenascin family of extracellular matrix proteins; Structural roles: tenascin‐X deficiency and Ehlers–Danlos syndrome; Tenascins as modulators of cell adhesion, migration, and growth; Role of tenascin‐C in inflammation; Regulation of tenascins by mechanical stress: implications for wound healing and regeneration; Association of tenascin‐C with cancer: antibodies as diagnostic and therapeutic tools; Conclusion and perspectives. Copyright © 2003 John Wiley & Sons, Ltd.Keywords
This publication has 154 references indexed in Scilit:
- Immunohistochemical expression of extracellular matrix components tenascin, fibronectin, collagen type IV and laminin in breast cancer: their prognostic value and role in tumour invasion and progressionEuropean Journal Of Cancer, 2002
- Coordinated regulation of procollagens I and III and their post-translational enzymes by dissipation of mechanical tension in human dermal fibroblastsEuropean Journal of Cell Biology, 2001
- Identification and Characterization of a Conformational Heparin-binding Site Involving Two Fibronectin Type III Modules of Bovine Tenascin-XJournal of Biological Chemistry, 2001
- Tenascin-Y, a Component of Distinctive Connective Tissues, Supports Muscle Cell GrowthExperimental Cell Research, 1999
- Identification of a Glioblastoma-Associated Tenascin-C Isoform by a High Affinity Recombinant AntibodyThe American Journal of Pathology, 1999
- Rapid and Reversible Regulation of Collagen XII Expression by Changes in Tensile StressExperimental Cell Research, 1999
- 131I Radioconjugated Antibodies for the Locoregional Radioimmunotherapy of High-grade Malignant Glioma: Phase I and II StudyActa Oncologica, 1999
- The expression of tenascin-C with the AD1 variable repeat in embryonic tissues, cell lines and tumors in various vertebrate speciesDifferentiation, 1997
- Tenascin‐C in serum: A questionable tumor markerInternational Journal of Cancer, 1995
- Phase I studies of treatment of malignant gliomas and neoplastic meningitis with131I-radiolabeled monoclonal antibodies anti-tenascin 81C6 and anti-chondroitin proteoglycan sulfate Me1-14 F (ab?)2-a preliminary reportJournal of Neuro-Oncology, 1995