Control-Initiated Case-Control Studies
- 1 March 1985
- journal article
- research article
- Published by Oxford University Press (OUP) in International Journal of Epidemiology
- Vol. 14 (1) , 130-134
- https://doi.org/10.1093/ije/14.1.130
Abstract
Greenland S (Division of Epidemiology, UCLA School of Public Health, Los Angeles, California 90024, USA). Control-initiated case-control studies. International Journal of Epidemiology 1985, 14: 130–134. In a control-initiated study the investigator begins with existing data on a non-diseased group and then selects cases to obtain comparison data; thus the usual order of case and control selection is reversed. This paper discusses the parallels and differences between control-initiated studies and more traditional case-control designs. Special attention is given to problems of selection bias and matching. A sample-size formula for control-initiated studies is also provided.Keywords
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