Studies of the Interference Phenomenon in Mustard-Treated Hosts

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Abstract
Summary: Injections of 0.1 or 0.2 ml of 0.025 M cyclo mustard into embryonated eggs before introduction of interfering virus resulted in diminution of interference. The effect produced by prior injections of cyclo mustard into the host was of relatively short duration. Diminution of interference resulting from prior injections of mustard into the host was not attributable to destruction of interfering virus. A similar diminution of interference occurred when mustard was injected after interfering virus, but the possibility of destruction of interfering virus was not investigated in this case. Studies of the temporal relationships in diminution of interference indicated that delayed injections of mustard were ineffectual in modification of interference 2 hours after introduction of inactivated virus into the host.