REM Syndrome (Reticular Erythematous Mucinosis)

Abstract
• A 50-year-old woman had cervical lymphadenopathy, swollen and waxylooking gums, and a diamond-shaped, reticular erythematous eruption on her back of eight years' duration. Histologic examination of the gingival tissue and skin showed round-cell infiltration around the small blood vessels and in the upper part of the dermis, and an extensive eosinophilic amorphous deposit throughout the dermis that stained with Alcian blue. The clinical and histologic features, although not identical, resembled those reported by Lischka and Orthenberger (1972)1 and later by Steigleder et al (1974).2,3 (Arch Dermatol 113:335-338, 1977)

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