EFFECTS OF SEX HORMONES ON THE BLOOD IN RATS

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Abstract
It has been shown previously that the male sex hormones exert a stimulating effect on heart, liver, and kidney tissues, and on the general body growth of rats, while the effect of female sex hormones is predominantly depressing [Korenchevsky & Ross, 1940; Korenchevsky & Hall, 1941; Korenchevsky, Hall, Burbank & Cohen, 1941]. To see whether the haemopoietic tissues would also be susceptible to these stimulating or depressing influences the effects of gonadectomy, oestrus, and sex hormones on red cell and haemoglobin levels were studied and are described in this paper. The clinical and experimental literature on the subject is largely contradictory, and a review of it is omitted at the Editors' request to economize space. METHODS The effects of gonadectomy and of various combinations of hormones on the blood were studied in seventy-two male rats and forty-three females. As far as possible, litter-mates were equally distributed between different groups. The

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