Alternative pathways for proline synthesis in mammalian cells
- 1 September 1977
- journal article
- Published by Springer Nature in Somatic Cell and Molecular Genetics
- Vol. 3 (5) , 529-538
- https://doi.org/10.1007/bf01539123
Abstract
Proline is synthesized in animal cells by way of two alternative pathways. Both of these pathways are functional in many cell lines. The relative contribution of a pathway to total proline synthesis may be altered by a mutational event. Differences in the developmental origin of a cell line are retained as differences in the pathways of proline synthesis.Keywords
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