Hyperthyroidism Following Secondary Hypothyroidism

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Abstract
A patient is reported who first sought treatment because of failing vision and hypogonadism secondary to a craniopharyngioma. This was surgically removed, and during the immediate postoperative period the patient developed hyperthermia in the absence of apparent infection, aphasia, hemiplegia and diabetes insipidus. He recovered from these and then became hypothyroid. About a year later, while taking desiccated thyroid, he developed hyperthyroidism with diffuse overactivity of the gland not suppressible with exogenous triiodothyronine. This sequence of events suggests that the hyperthy-roidism resulted from an extrathyroidal disorder in this patients.

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