Microdialysis Assessment of Microfibrous Collagen Containing a P-Glycoprotein-Mediated Transport Inhibitor, Cyclosporine A, for Local Delivery of Etoposide
- 1 January 1996
- journal article
- Published by Springer Nature in Pharmaceutical Research
- Vol. 13 (10) , 1565-1569
- https://doi.org/10.1023/a:1016096016642
Abstract
Purpose. This study was designed to assess a local drug delivery system of an anticancer agent, etoposide (VP-16), using microfibrous collagen as a drug carrier. For this objective, the microdialysis...Keywords
This publication has 13 references indexed in Scilit:
- O-demethylation of epipodophyllotoxins is catalyzed by human cytochrome P450 3A4.1994
- Molecular Targets in Oncology: Implications of the Multidrug Resistance GenePharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, 1993
- In Vivo Microdialysis Sampling in the Bile, Blood, and Liver of Rats to Study the Disposition of PhenolPharmaceutical Research, 1993
- Alteration of etoposide pharmacokinetics and pharmacodynamics by cyclosporine in a phase I trial to modulate multidrug resistance.Journal of Clinical Oncology, 1992
- Phase I trial of etoposide with cyclosporine as a modulator of multidrug resistance.Journal of Clinical Oncology, 1992
- Effect of Cyclosporine on Colchicine Secretion by A Liver Canalicular Transporter Studied In VivoHepatology, 1992
- An Application of Microdialysis to Drug Tissue Distribution Study: In Vivo Evidence for Free-Ligand Hypothesis and Tissue Binding of .BETA.-Lactam Antibiotics in Interstitial Fluids.Journal of Pharmacobio-Dynamics, 1992
- The function of Gp170, the multidrug resistance gene product, in rat liver canalicular membrane vesiclesJournal of Biological Chemistry, 1989
- METABOLISM OF CYCLOSPORINE-A .4. PURIFICATION AND IDENTIFICATION OF THE RIFAMPICIN-INDUCIBLE HUMAN-LIVER CYTOCHROME-P-450 (CYCLOSPORINE-A OXIDASE) AS A PRODUCT OF P450IIIA GENE SUBFAMILY1989
- Cyclosporin A reverses vincristine and daunorubicin resistance in acute lymphatic leukemia in vitro.Journal of Clinical Investigation, 1986