Effect of Adrenocortical Steroids on Duration of Pentothal Anesthesia in Adrenalectomized Mice
- 1 November 1953
- journal article
- research article
- Published by Frontiers Media SA in Experimental Biology and Medicine
- Vol. 84 (2) , 308-310
- https://doi.org/10.3181/00379727-84-20628
Abstract
Summary The effects of the administration of cortisone acetate, hydrocortisone acetate and DOCA on the duration of pentothal anesthesia in adrenalectomized female mice were ascertained. Adrenalectomy induced a highly significant prolongation in the duration of pentothal anesthesia. Pretreatment of cortisone acetate and hydrocortisone acetate returned the anesthesia time to normal level in adrenalectomized mice, while DOCA and saline had no effect.Keywords
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