Dystroglycan: a multifunctional adaptor protein
- 26 October 2005
- journal article
- Published by Portland Press Ltd. in Biochemical Society Transactions
- Vol. 33 (6) , 1254-1255
- https://doi.org/10.1042/bst0331254
Abstract
Dystroglycan, a ubiquitous membrane-spanning cell adhesion molecule, is a crucial link between the actin cytoskeleton and the extracellular matrix. With a wide expression pattern and multiple interacting proteins, not only is dystroglycan now thought to be important as a structural molecule but also new research has suggested that it has a role in cell signalling, cytoskeleton reorganization and as a potential tumour suppressor.Keywords
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