Potential Role of TNF-α in the Pathogenesis of Insulin Resistance and Type 2 Diabetes
Top Cited Papers
- 1 August 2000
- journal article
- review article
- Published by Elsevier in Trends in Endocrinology & Metabolism
- Vol. 11 (6) , 212-217
- https://doi.org/10.1016/s1043-2760(00)00272-1
Abstract
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This publication has 52 references indexed in Scilit:
- Transmembrane Tumor Necrosis Factor (TNF)-α Inhibits Adipocyte Differentiation by Selectively Activating TNF Receptor 1Published by Elsevier ,1999
- An in Vivo Model for Elucidation of the Mechanism of Tumor Necrosis Factor- (TNF- )-Induced Insulin Resistance: Evidence for Differential Regulation of Insulin Signaling by TNF-Endocrinology, 1998
- High Fat Diets Elevate Adipose Tissue-Derived Tumor Necrosis Factor- ActivityEndocrinology, 1997
- Acute and Chronic Exposure to Tumor Necrosis Factor- Fails to Affect Insulin-Stimulated Glucose Metabolism of Isolated Rat Soleus MuscleEndocrinology, 1997
- Molecular basis for insulin resistance: elevated serine/threonine phosphorylation of IRS-1 and IRS-2 inhibits their binding to the juxtamembrane region of the insulin receptor and impairs their ability to undergo insulin-induced tyrosine phosphorylationExperimental and Clinical Endocrinology & Diabetes, 1997
- Tumor Necrosis Factor Promotes Phosphorylation and Binding of Insulin Receptor Substrate 1 to Phosphatidylinositol 3-Kinase in 3T3-L1 AdipocytesJournal of Biological Chemistry, 1996
- Linkage between obesity and a marker near the tumor necrosis factor-alpha locus in Pima Indians.Journal of Clinical Investigation, 1995
- Increased adipose tissue expression of tumor necrosis factor-alpha in human obesity and insulin resistance.Journal of Clinical Investigation, 1995
- The expression of tumor necrosis factor in human adipose tissue. Regulation by obesity, weight loss, and relationship to lipoprotein lipase.Journal of Clinical Investigation, 1995
- Adipose Expression of Tumor Necrosis Factor-α: Direct Role in Obesity-Linked Insulin ResistanceScience, 1993