Mediation of Immunity to Tumor Isografts in Mice by Heterologous Ribonucleic Acid
- 24 April 1970
- journal article
- other
- Published by American Association for the Advancement of Science (AAAS) in Science
- Vol. 168 (3930) , 492-493
- https://doi.org/10.1126/science.168.3930.492
Abstract
The growth of tumor isografts in inbred mice is inhibited by intraperitoneal injections of syngeneic spleen incubated, in vitro, with ribonucleic acid extracted from guinea pigs immunized with the same mouse tumor. This inhibition is partially tumor-specific. Treatment with ribonuclease abolishes the response.Keywords
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