Influence of DDT, DDVP and malathion on FSH, LH and testosterone serum levels and testosterone concentration in testis
- 1 August 1977
- journal article
- research article
- Published by Springer Nature in Bulletin of Environmental Contamination and Toxicology
- Vol. 18 (2) , 231-242
- https://doi.org/10.1007/bf01686072
Abstract
Summary Groups of adult male rats were treated with DDT, DDVP or malathion orally for two or three weeks. Body weight and testis weight did not change. FSH and LH levels in serum also remained unchanged, whereas that of testosterone was decreased by DDT. This substance also diminished the concentration of testosterone in the testis. Therefore, the previously observed damage to spermatogenesis by DDT are assumed to be caused by a lack of androgens. Those following treatment with DDVP or malathion seem to be due to a direct cytotoxic effect.Keywords
This publication has 8 references indexed in Scilit:
- Damage to spermatogenesis in juvenile rat treated with DDVP and malathionBulletin of Environmental Contamination and Toxicology, 1976
- FSH AND TESTOSTERONE LEVELS IN PLASMA OF JUVENILE MALE RATS AFTER APPLICATION OF OVINE FSH, HCG AND PMS AT DIFFERENT AGES1976
- The effect of DDT on spermatogenesis of the juvenile ratBulletin of Environmental Contamination and Toxicology, 1975
- Alterations of the seminiferous epithelium and the leydig cells of the rat testis after the application of dichlorvos (DDVP)Bulletin of Environmental Contamination and Toxicology, 1974
- DDT Homologues: Estrogen-Like Effects on the Vagina, Uterus and Pituitary of the RatEndocrinology, 1972
- Zinc-DDT Interrelationships in Growth and Reproduction in the RatJournal of Nutrition, 1972
- INFLUENCE OF CHLORINATED HYDROCARBONS AND ORGANOPHOSPHATE INSECTICIDES ON METABOLISM OF STEROIDSAnnals of the New York Academy of Sciences, 1969
- Über die Alkylierungseigenschaften von ThiophosphorsäurealkylesternAngewandte Chemie, 1965