A novel HLA‐DR12 allele (DRB1*1206) found in a Korean B‐cell line
- 1 May 1999
- journal article
- research article
- Published by Wiley in Tissue Antigens
- Vol. 53 (5) , 516-518
- https://doi.org/10.1034/j.1399-0039.1999.530510.x
Abstract
At least 6 HLA‐DRB1*12 alleles have been identified to date with nucleotide polymorphism occurring at codons 37, 57–58, 60, 67, 85 and 87. In this report, we describe the identification of another new HLA‐DRB1*12 allele: DRB1*1206. This novel allele was found in an Epstein‐Barr virus (EBV)‐transformed Korean B‐cell line “K‐KT” having the HLA‐phenotype A3, 24; B44, 61; Cw3; Bw4, 6; DR12, 13 during full‐length cDNA isolation for cell line characterization and for production of HLA‐DR recombinant proteins. The allele was identified initially by cycle sequencing of subcloned HLA‐DRB full‐length cDNA Note.Keywords
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