Sample loss and its control with internal‐loop injection valves in supercritical fluid chromatography

Publisher Website
Google Scholar
Abstract
Large losses of solute can occur with internal‐loop injection valves, especially if the assignments of the injection and waste ports are reversed and a highly volatile diluent is used. However, good performance can be obtained even with the port assignments reversed and with a volatile diluent if a flow restrictor is attached to the waste port.