Antiphagocytic Effects of Staphylococcal Protein A
Open Access
- 1 December 1969
- journal article
- Published by Oxford University Press (OUP) in The Journal of Immunology
- Vol. 103 (6) , 1405-1410
- https://doi.org/10.4049/jimmunol.103.6.1405
Abstract
Strains of Staphylococcus aureus possessing large amounts of protein A tended to resist phagocytosis more than strains that contain lesser amounts or none of this protein. Protein A extracted from S. aureus inhibited phagocytosis of both S. aureus and Escherichia coli in in vitro phagocytosis systems. The antiphagocytic effect was produced by nonspecific reaction of protein A with the Fc piece of γG globulin.Keywords
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