Vitamin C in CC14 Hepatotoxicity-A Preliminary Report
- 1 February 1994
- journal article
- Published by SAGE Publications in Human & Experimental Toxicology
- Vol. 13 (2) , 107-109
- https://doi.org/10.1177/096032719401300208
Abstract
1 The hepatotoxic effect of CC14 was studied in the rat by using 3 well established liver function tests (plasma glucose, bilirubin and proteins) as indices of hepatic integrity.2 The protective effect of vitamin C against this hepatotoxicity was also investigated.3 CC 14 (8 ml kg-1body weight) caused a decrease in the levels of plasma conjugated bilirubin, glucose and protein.4 Vitamin C (2 g kg-1body weight) prevented liver damage induced by CC14. The possible mechanisms of protection are highlighted.Keywords
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