Exclusion of Usher syndrome gene from much of chromosome 4
- 1 January 1989
- journal article
- research article
- Published by S. Karger AG in Cytogenetic and Genome Research
- Vol. 50 (2-3) , 102-106
- https://doi.org/10.1159/000132733
Abstract
Usher syndrome is an autosomal recessive disease characterized by dual sensory impairments; affected individuals are born with a sensorineural hearing loss and ultimately lose their sight as retinitis pigmentosa develops. Conventional protein markers previously tested in a Louisiana Acadian kindred suggested tentative linkage to vitamin D-binding protein on chromosome 4. DNA linkage studies do not confirm this linkage relationship and exclude much of chromosome 4 as the site of the Usher syndrome gene in these families.This publication has 10 references indexed in Scilit:
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