MARKERS FOR CARDIOVASCULAR AND RENAL MORBIDITY: EXPECTATIONS FOR AN INTERVENTION PROGRAMME IN AN AUSTRALIAN ABORIGINAL COMMUNITY

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Abstract
1 Australian Aborigines have high rates of both cardiovascular mortality and renal failure and the usual male dominance in these conditions is respectively reduced and effaced. 2 In one Aboriginal community, we have demonstrated a strong association between albuminuria and cardiovascular risk factors and a relationship of both with insulin resistance, which is more pronounced in females than males. 3 We propose that albuminuria is a component of Syndrome X and that reduction in levels of albuminuria should prove to be a useful marker of effectiveness in treatment programmes targeting cardiovascular risk as well as renal disease.