Thalidomide-induced peripheral neuropathy. Effect of serum factor on nerve cultures
- 1 November 1984
- journal article
- research article
- Published by American Medical Association (AMA) in Archives of Dermatology
- Vol. 120 (11) , 1466-1470
- https://doi.org/10.1001/archderm.120.11.1466
Abstract
Sensory neuropathies developed in 3 of 4 patients with prurigo nodularis who had been treated with thalidomide. Serum samples of the patients who had neuropathy produced morphologic changes in cultured dorsal root ganglion cells. These observed changes support the postulate that thalidomide induces primary neuronal degeneration.This publication has 0 references indexed in Scilit: