Metformin directly inhibits androgen production in human thecal cells

This publication has 37 references indexed in Scilit:

• Menstrual Cyclicity After Metformin Therapy in Polycystic Ovary Syndrome
  Obstetrics & Gynecology, 1997
• Decreases in Ovarian Cytochrome P450c17α Activity and Serum Free Testosterone after Reduction of Insulin Secretion in Polycystic Ovary Syndrome
  New England Journal of Medicine, 1996
• Inhibin and activin differentially regulate androgen production and 17α-hydroxylase expression in human ovarian thecal-like tumor cells
  Journal of Endocrinology, 1996
• Excessive insulin receptor serine phosphorylation in cultured fibroblasts and in skeletal muscle. A potential mechanism for insulin resistance in the polycystic ovary syndrome.
  Journal of Clinical Investigation, 1995
• Insulin secretory defects in polycystic ovary syndrome. Relationship to insulin sensitivity and family history of non-insulin-dependent diabetes mellitus.
  Journal of Clinical Investigation, 1995
• Insulin Resistance and Ovarian Hyperandrogenism
  The Endocrinologist, 1992
• Polycystic ovary syndrome: Interaction of follicle stimulating hormone and polypeptide growth factors in oestradiol production by human granulosa cells
  The Journal of Steroid Biochemistry and Molecular Biology, 1991
• HETEROGENEITY OF THE POLYCYSTIC OVARY SYNDROME: CLINICAL, ENDOCRINE AND ULTRASOUND FEATURES IN 556 PATIENTS
  Clinical Endocrinology, 1989
• Insulin administration alters gonadal steroid metabolism independent of changes in gonadotropin secretion in insulin-resistant women with the polycystic ovary syndrome.
  Journal of Clinical Investigation, 1989
• Cloning and Sequence of the Human Gene for P450cl7 (Steroid 17α-Hydroxylase/17,20 Lyase): Similarity with the Gene for P450c21
  DNA, 1987