When drugs are infused, it is often necessary to minimize the volume of fluid delivered. Fluid delivery rates of 1 cm3/h or less are frequently desirable; however, the accurate metering of fluids at such low flow rates to the human body has been difficult to accomplish. The metering devices most commonly used to control flow rate from a constant-pressure source have been micrometer valves, clamped tubes, capillaries, and porous plugs. Each of these devices has specific disadvantages : micrometer valves are expensive and bulky, clamped tubes are not stable for long-term infusion and present a hazard of greatly fluctuating flow rates, capillary tubes are subject to particle blockage and are not adjustable, and porous plugs suffer from lack of adjustability. Recently a valve made of extruded silicone rubber rod with axial holes was reported to yield stable flow rates; it was adjusted by placement in a plastic clamp. A new low-infusion-rate metering system has been developed to overcome the above deficiencies. This system consists of axially aligned polyurethane fibers contained within the lumen of a length of silicone rubber tubing. The fibers fill the lumen to the extent that they are subjected to a compressive hoop stress by the tubing. The assembly represents two elastomeric materials in states of strain, exerting equal and opposite stresses on each other. The elastomeric tubular assembly is contained in a rigid, adjustable, U-shaped enclosure that controls the deformation of the assembly. While other elastomeric materials would be suitable for the elastomeric valving system, we report here on our experience with polyurethane fibers and silicone rubber tubing. These materials were selected for their expected compatibility with most aqueous drugs and their availability.